Various sources have reported on how often misconduct is detected, but with different results:
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PubMed retractions : 0.02%
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US Office of Research Integrity: 0.01-0.001% (1 in 10,000/100,000 scientists)
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Image manipulation in Journal of Cell Biology: 1% (8/800)
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Food and Drug Administration audit (investigators guilty of serious scientific misconduct): 2%