Outcome Reporting Among Drug Trials Registered in ClinicalTrials.gov

A paper published in the Annals of Internal Medicine this week looked at associations between the funding sources of 546 registered trials of drugs in 5 commonly prescribed classes and published outcomes, using data from clinicaltrials.gov. The full study is not freely available, but from the abstract, the results show that "Industry-funded trials reported favorable outcomes in 85.4% of publications, compared with 50.0% for government-funded trials and 71.9% for nonprofit or nonfederal organization–funded trials."

This paper adds to the growing literature on the association of funding source and outcomes, especially in medical studies.